The PureMuze Journal

Evidence-based, clinician-reviewed guidance on GLP-1, metabolism and hormones for women in midlife. No hype, no fear-mongering, just clear answers.

Menopause & Metabolism · 8 min read

GLP-1 After 40: Why Weight Loss Changes

Estrogen decline can roughly halve your body's own GLP-1. Here's what that means for weight loss after 40 and what actually helps.

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GLP-1 Basics · 9 min read

Semaglutide vs. Tirzepatide: An Honest Comparison

Two medications, two mechanisms. How they differ, what the research says for women and how a clinician decides which fits you.

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Hormones · 6 min read

Why Midlife Weight Settles Around the Middle

Visceral fat, cortisol, sleep and shifting hormones, the real reasons the scale and your shape change after 35.

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